Dr. Robert Stewart -- Purdue University School of Health Sciences Faculty

Purdue University (calendar)
School of Health Sciences
Faculty

Robert D. Stewart, Ph.D.
Associate Professor of Health Sciences
Director, Undergraduate Program in Radiological Health

School of Health Sciences
550 Stadium Mall Drive
West Lafayette, IN 47907-2051
(765) 494-1444 voice
(765) 496-1377 fax
(765) 494-0737 secretary
trebor@purdue.edu

Spring 2008: Post-doctoral positions (none at this time)
Spring 2008: Undergraduate and graduate student internships (none at this time)

Education

B.S. Nuclear Engineering, Kansas State University, Manhattan, KS (1988).

M.S. Nuclear Engineering, Kansas State University, Manhattan, KS (1990).

Ph.D. Mechanical and Nuclear Engineering, Kansas State University, Manhattan, KS (1997).

Professional Experience

2006-present

Associate Professor (tenured). Purdue University School of Health Sciences.

2003-2006

Assistant Professor (courtesy). Oregon State University Nuclear Engineering and Radiation Health Physics.

2002-2006

Assistant Professor (tenure track). Purdue University School of Health Sciences.

1997 - 2002

Senior Scientist. Radiation and Biophysics Research, Pacific Northwest National Laboratory

Summer 1998

Adjunct Faculty. Math Department, Columbia Basin College.

1990 - 1993

Research Scientist. Dosimetry Research and Technology, Pacific Northwest National Laboratory.

Teaching (Received the 2005 and 2006 Robert R. Landolt Teaching Award, Nominated for the Murphy Teaching Award in 2004, 2005 and 2006)

HSCI 101 Introduction to the Health Sciences Professions (Guest lecturer)
ENGR 103 Introduction to Engineering Careers (Guest Lecturer)
HSCI 312 Radiation Science Fundamentals (Instructor)
HSCI 540 Radiation Biology (Instructor)
HSCI 590A Special Topics: Radiological Emergency Management (Co-Instructor)
HSCI 590B Special Topics: Computational Methods in Radiological Science I (Instructor)
HSCI 590C Special Topics: Computational Methods in Radiological Science II (Instructor)

Mentoring
Faculty Advisor for the Purdue Branch of the Health Physics Society (PBHPS)

Research Interests

Mechanistic modeling of biological systems, e.g., see the Monte Carlo Damage Simulation (MCDS), Monte Carlo Excision Repair (MCER), and Virtual Cell software.

Radiation physics, dosimetry and microdosimetry.

Monte Carlo and discrete ordinates radiation transport methods.

Radiation therapy for the treatment of cancer (emphasis on biological optimization of treatment plan designs).

Mathematical modeling, numerical analysis, optimization techniques, and high-performance computing.

Grants

Service-Learning Faculty Development Grant, Purdue University 2007-2008
Monte Carlo Simulation of 90Y Microsphere Deposition in the Vasculature of Normal and Malignant Liver Tissue. Summer Faculty Grant, Purdue Research Foundation, R.D. Stewart, Principal Investigator. May-August 2007.
Towards Constructing and Testing a Virtual Tissue. Office of Science (BER), U.S. Department of Energy, Grant DE-FG02-03ER63665. R.D. Stewart, Principal Investigator. September 2003-August 2006.
Kinetic Modeling of Damage Repair, Genome Instability, and Neoplastic Transformation. Office of Science (BER), U.S. Department of Energy, Grant DE-FG02-03ER63541. R.D. Stewart, Principal Investigator. October 2001 - December 2005.
Molecular Energetics of Clustered Damage sites. Subcontract from Pacific Northwest National Laboratory. January 2003 - August 2005 (Subcontract is associated with a larger DOE Office of Science project of the same name. M. Dupuis, Principal Investigator).

Professional Affiliations

American Association of Physicists in Medicine
American Nuclear Society
American Association for the Advancement of Science
Health Physics Society
Radiation Research Society. Physics Councilor (2005-2008) and member of the Constitution and By-Laws Committee (2004-2005). Associate Editor for the journal Radiation Research (2007-2011).

Selected Presentations (complete list)

RD Stewart, Biologically Guided Radiation Therapy (BGRT). Invited presentation, 3rd annual McGill Workshop on Monte Carlo Techniques in Radiotherapy Delivery and Verification, McGill University, Montreal, Canada, May 29-June 1, 2007.
VA Semenenko and RD Stewart, Effects of intercellular signal-mediated cell death and neoplastic transformation on transformation frequency at low doses of ionizing radiation. Oral presentation and poster presented at the 53^st Annual Meeting of the Radiation Research Society in Philadelphia, Pennsylvania, USA, November 5-8, 2006.
R.D. Stewart. Induction, Repair and Biological Consequences of Clustered DNA Lesions. Continuing Education Lecture (CEL-8), 51st Annual Meeting Health Physics Society. Providence, Rhode Island, June 25-29 (2006).
R.D. Stewart and R.K. Ratnayake. Implications of intercellular signaling for the shapes of dose-response relationships. DOE Low Dose Program Workshop V, Washington DC, April 25-27, 2005.

Selected Publications (complete list)

D.J. Carlson, R.D. Stewart, V.A. Semenenko and G.A. Sandison, Combined use of Monte Carlo DNA damage simulations and deterministic repair models to examine putative mechanisms of cell killing. Rad. Res. 169, 447-459 (2008)

Y Hsiao and R.D. Stewart, Monte Carlo Simulation of DNA Damage Induction by X-rays and Selected Radioisotopes. Phys. Med. Biol. 53, 233-244 (2008)

X.A. Li, J.Z. Wang, R.D. Stewart, S.J. DiBiase, D. Wang and C.A. Lawton, Designing equivalent treatment regimens for prostate radiotherapy based on equivalent uniform dose, British Journal of Radiology, 81, 59-68(2008).

R.D. Stewart and X.A. Li, BGRT: Biologically Guided Radiation Therapy – the future is fast approaching! Medical Physics 34, 3739-3751 (2007). Also selected for publication in the Virtual Journal of Biological Physics Research (http://www.vjbio.org/), Volume 14(6), September 15, 2007

Z. Liu, W.V. Prestwich, R.D. Stewart, S.H. Byuna, C.E. Mothersill, F.E. McNeill, and C.B. Seymour, Effective Target Size for the Induction of Bystander Effects in Medium Transfer Experiments. Radiat. Res. 168, 627-630 (2007).

D.J. Carlson, R.D. Stewart and V.A. Semenenko, Effects of oxygen on intrinsic radiation sensitivity – a test of the relationship between aerobic and hypoxic linear-quadratic (LQ) model parameters. Medical Physics 33(9), 3105-3115 (2006)

R.D. Stewart, R.K. Ratnayake, and K. Jennings. Microdosimetric model for the induction of cell killing through medium-borne signals. Radiat. Res. 165, 460-469 (2006).

V.A. Semenenko and R.D. Stewart. Fast Monte Carlo simulation of DNA damage formed by electrons and light ions. Phys. Med. Biol. 51(7), 1693-1706 (2006)

V.A. Semenenko and R.D. Stewart. Monte Carlo Simulation of Base and Nucleotide Excision Repair of Clustered DNA Damage Sites. II. Comparisons of Model Predictions to Measured Data. Radiat. Res. 164, 194-201 (2005).

V.A. Semenenko, R.D. Stewart, E.J. Ackerman. Monte Carlo Simulation of Base and Nucleotide Excision Repair of Clustered DNA Damage Sites. I. Model Properties and Predicted Trends. Radiat. Res. 164, 180-193 (2005).

D.J. Carlson, R.D. Stewart, X.A. Li, K. Jennings, J.Z. Wang, and M. Guerrero. Comparison of in vitro and in vivo α/β ratios for prostate cancer. Phys. Med. Biol. 49, 4477-4491 (2004).

V.A. Semenenko and R.D. Stewart. A fast Monte Carlo algorithm to simulate the spectrum of DNA damages formed by ionizing radiation. Radiat Res. 161(4), 451-457 (2004).

J.Z. Wang, X.A. Li., W. D’Souza, R.D. Stewart. Impacts of prolonged dose-delivery time on tumor control: a note of caution for IMRT, Int. J. Radiat. Oncol. Biol. Phys. 57(2), 543-552 (2003).

M. Guerrero, R.D. Stewart, J. Wang, and X.A. Li. Equivalence of the Linear-Quadratic and Two-Lesion Kinetic Models. Phys. Med. Biol. 47, 3197–3209 (2002).

J.M. Malard and R.D. Stewart, Distributed Dynamic Hash Tables Using IBM LAPI. Supercomputing 2002.

D.J. Strom, R.D. Stewart, and J.C. McDonald, Spectral Emissions and Dosimetry of Metal Tritide Particulates. Radiat. Prot. Dosim. 98(4), 389-400 (2002).

R.D. Stewart, W.E. Wilson, J.C. McDonald, and D.J. Strom, Microdosimetric Properties of Ionizing Electrons in Water: A Test of the PENELOPE code system. Phys. Med. Biol. 47(1), 79-88 (2002).

R.D. Stewart, Two-Lesion Kinetic Model of DSB Rejoining and Cell Killing. Radiat. Res. 156(4), 365-378 (2001).

R.D. Stewart, On the Complexity of the DNA Damages Created by Endogenous Processes. Radiat. Res. 152(1), 101-104 (1999).

Last Updated: March 26, 2008